{"id":175,"date":"2015-10-17T12:00:42","date_gmt":"2015-10-17T10:00:42","guid":{"rendered":"http:\/\/aireligion.org\/?p=175"},"modified":"2015-10-17T12:00:42","modified_gmt":"2015-10-17T10:00:42","slug":"artificial-intelligence-is-making-better-drugs","status":"publish","type":"post","link":"https:\/\/aireligion.org\/?p=175","title":{"rendered":"Artificial intelligence is making better drugs"},"content":{"rendered":"<p class=\"intro\"><img class=\" ssrMultiImg\" src=\"http:\/\/cdni.wired.co.uk\/1920x1280\/k_n\/Niven%20R%20Narain%20001.jpg\" alt=\"Niven R Narain\" data-aspectratio=\"1.5\" data-maxheight=\"1280\" data-maxwidth=\"1920\" data-srcsizedata=\"{&quot;values&quot;:[{&quot;width&quot;:1920,&quot;height&quot;:1280,&quot;url&quot;:&quot;http:\/\/cdni.wired.co.uk\/1920x1280\/k_n\/Niven%20R%20Narain%20001.jpg&quot;}]}\" \/><\/p>\n<p class=\"intro\"><span class=\"caption-title\">Niven R Narain<br \/>\n<\/span>AI Drug Developer<\/p>\n<p class=\"intro\">WIRED 2015 is our annual two-day celebration of the innovators, inventors, artists and entrepreneurs who are reinventing our world. For more from the event, head over to our <a href=\"http:\/\/www.wired.co.uk\/wired2015\">WIRED 2015 hub<\/a>.<\/p>\n<p>Creating new drugs is expensive.\u00a0On average, it takes $2.6bn (\u00a31.7bn) and between ten and 15 years to get a <a href=\"http:\/\/www.wired.co.uk\/drugs\">drug<\/a> from planning to pharmacist, according to some estimates. And that&#8217;s because current methods are so untargeted &#8212; for every 100 drugs that reach first stage clinical trials, only one goes on to become an actual <em>treatment<\/em>.<\/p>\n<p><!--more--><\/p>\n<aside class=\"quoteBlob pullToSide ssrPullToSide\">\n<blockquote class=\"quote\"><p>&#8220;Precision medicine is going to be the future&#8221;<\/p><\/blockquote>\n<div class=\"author\">\n<p class=\"name\">Niven Narain, <span class=\"company\">co-founder, president and chief technology officer, Berg<\/span><\/p>\n<\/div>\n<\/aside>\n<p>&#8220;In any other industry in the world, we would all be fired,&#8221; said<a href=\"https:\/\/twitter.com\/niven_narain\" target=\"_blank\">Niven Narain<\/a>, co-founder, president and chief technology officer at <a href=\"http:\/\/www.berghealth.com\/\" target=\"_blank\">Berg<\/a>, a company that&#8217;s pairing <a href=\"http:\/\/www.wired.co.uk\/artificial-intelligence\">artificial intelligence<\/a> with medical research to create more precise treatments.<\/p>\n<figure class=\"imageBlob landscape keepInline hasCaption hasDescription\" data-asset-id=\"542714\">\n<div class=\"stickyInner\">\n<div class=\"stickyInner\"><\/div>\n<\/div><figcaption class=\"image-caption\"><span class=\"image-credits\">Vincent Whiteman WIRED<\/span><\/figcaption><\/figure>\n<p>&#8220;As an industry we have to do better but we have to go back to biology,&#8221; Narain explained. Berg&#8217;s approach is to create &#8216;maps&#8217; of patients, creating huge quantities of data from large sample sizes, and mine that data for practical ways to make drugs cheaper, and quicker.<\/p>\n<div id=\"inreadAdPlaceholderOuter\"><\/div>\n<p>&#8220;We&#8217;re creating maps on every single patient. We&#8217;re taking all the complex <a href=\"http:\/\/www.wired.co.uk\/biology\">biological<\/a> information and transforming it into something that&#8217;s representative of the patient in the form of maps,&#8221; he told the audience at WIRED2015.<\/p>\n<p>These <a href=\"http:\/\/www.wired.co.uk\/maps\">maps<\/a> take into account biological, clinical and real world information, building a narrative around each patient.<\/p>\n<p><a class=\"thumb landscape\" href=\"http:\/\/www.wired.co.uk\/news\/archive\/2015-10\/16\/niven-r-narain-ai-drugs-wired2015\/viewgallery\/542711\" target=\"ArticleGalleryIframe\" data-asset-id=\"542711\"><img loading=\"lazy\" class=\"\" src=\"http:\/\/cdni.wired.co.uk\/1920x1280\/k_n\/Niven%20R%20Narain%20005.jpg\" alt=\"View gallery\" width=\"1920\" height=\"1280\" data-aspectratio=\"1.5\" data-maxheight=\"1280\" data-maxwidth=\"1920\" data-srcsizedata=\"{&quot;values&quot;:[{&quot;width&quot;:1920,&quot;height&quot;:1280,&quot;url&quot;:&quot;http:\/\/cdni.wired.co.uk\/1920x1280\/k_n\/Niven%20R%20Narain%20005.jpg&quot;}]}\" \/><\/a><\/p>\n<p>&#8220;Precision <a href=\"http:\/\/www.wired.co.uk\/medicine\">medicine<\/a> is going to be the future,&#8221; Narain argued. &#8220;We [need to] move away from this one size fits all [approach], because 90 percent of people with pancreatic <a href=\"http:\/\/www.wired.co.uk\/cancer\">cancer<\/a> fail the first line of therapy.&#8221;<\/p>\n<div class=\"relatedArticle keepInline relatedArticleNormal imageLandscape\"><\/div>\n<p>With the help of artificial intelligence, Berg and his team have developed a process to reactivate mitochondria in dying cells, stopping them from becoming cancerous.\u00a0The drug, <a href=\"http:\/\/www.berghealth.com\/clinical_disease_cancer.html\">BPM31510<\/a>, restarts the metabolisation of glucose and allows the body to harmlessly pass the problem cells. This drug, and the speed of its development, were only possible because of artificial intelligence and data analysis, Narain argued.<\/p>\n<p>And the field is progressing quickly; Narain is confident that doctors will be prescribing drugs developed from similar systems in the next couple of years.<\/p>\n<div id=\"ArticleBottom_GptOuter\" class=\"mpuOrSky cnGptMinimiseJumpiness cnGptAlign_HorizontalCentered cnGptNotFullWidthSlot cnGptSlotOuter\" data-incontentplaceholderid=\"incontentAd_last\">\u00a0&#8220;Artificial intelligence and the next generation of biology will allow us to participate in our own health,&#8221; he said.<\/div>\n<div class=\"mpuOrSky cnGptMinimiseJumpiness cnGptAlign_HorizontalCentered cnGptNotFullWidthSlot cnGptSlotOuter\" data-incontentplaceholderid=\"incontentAd_last\"><\/div>\n<div class=\"mpuOrSky cnGptMinimiseJumpiness cnGptAlign_HorizontalCentered cnGptNotFullWidthSlot cnGptSlotOuter\" data-incontentplaceholderid=\"incontentAd_last\"><a href=\"http:\/\/www.wired.co.uk\/news\/archive\/2015-10\/16\/niven-r-narain-ai-drugs-wired2015\">http:\/\/www.wired.co.uk\/news\/archive\/2015-10\/16\/niven-r-narain-ai-drugs-wired2015<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Niven R Narain AI Drug Developer WIRED 2015 is our annual two-day celebration of the innovators, inventors, artists and entrepreneurs who are reinventing our world. For more from the event, head over to our WIRED 2015 hub. Creating new drugs is expensive.\u00a0On average, it takes $2.6bn (\u00a31.7bn) and between ten and 15 years to get &hellip; <a href=\"https:\/\/aireligion.org\/?p=175\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Artificial intelligence is making better drugs<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3,2],"tags":[],"_links":{"self":[{"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/posts\/175"}],"collection":[{"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aireligion.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=175"}],"version-history":[{"count":1,"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/posts\/175\/revisions"}],"predecessor-version":[{"id":176,"href":"https:\/\/aireligion.org\/index.php?rest_route=\/wp\/v2\/posts\/175\/revisions\/176"}],"wp:attachment":[{"href":"https:\/\/aireligion.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aireligion.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aireligion.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}